A recent study at Massachusetts General Hospital in Boston linked anorexia to loss of bone density in young women. Published in The Annals of Internal Medicine, the study suggests that even estrogen cannot counteract the damage to bones caused by anorexia. In the 130 anorexic women studied, 92 percent showed enough bone loss to double their risk of fracture, and 38 percent were diagnosed with osteoporosis. Women across the study showed the same rate of bone loss, despite the fact that about 25 percent were taking estrogen. Women with lower weights experienced the most extreme bone density loss, and calcium and vitamin D did not improve the problem.